Mixed-lymphocyte reaction as a measure of immunological competence of lymphocytes from patients with Crohn's disease
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چکیده
منابع مشابه
The multiple mixed lymphocyte reaction: variables important in the test as a measure of lymphocyte competence in man.
In order to utilize the mixed lymphocyte reaction (MLR) as an assay of T-lymphocyte competence, pools of target lymphocytes obtained from different individuals are used to increase the magnitude and decrease the variation of the in vitro response. We evaluated variations in MLR response due to variations in target cell populations. Response increased with an increased target/responder cell r...
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T helper and suppressor cell control of autologous immunoglobulin production was measured in 14 patients with Crohn's disease (CD) using autologous B cells or monocytes to stimulate regulatory T-cell activity. A pronounced defect in suppressor cell function was observed in the patient group but not in matched controls irrespective of whether B cells or monocytes were used as the stimulus. This ...
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ژورنال
عنوان ژورنال: Gut
سال: 1974
ISSN: 0017-5749
DOI: 10.1136/gut.15.1.24